Kicking 10 majors in the first half, Bunbury moved out to a 58-point lead over Eaton at the main break.
The Bulldogs returned to the winners' circle in style with a 15.10.100 to 1.0.6 win.
South Bunbury remains in contention for the 2019 South West Football League - Women's premiership title, after its 16-point win over Carey Park.
The Tigers hit the ground running in the opening term, before claiming a nine-point lead at the first change.
The league leaders dominated the second term and kept the Panthers scoreless in the first half.
Ahead by 16 at three quarter time, South Bunbury went on to nab a 3.5.23 to 1.1.7 victory in Round Four. Bethany Bond, Kristy Jetta, and Amber Boyd booted the Tigers' three goals, before Nadia Davis kicked one for Carey Park.
Busselton moved up to third on the ladder with a 12-point win over the Eagles at the Collie Recreation Ground on Saturday afternoon. Collie was scoreless throughout the first three quarters, while the Magpies were in cruise control.
The visitors claimed their third win of the season with a 2.8.20 to 1.2.8 result.
The clash between Harvey and Harvey-Brunswick-Leschenault was called off, out of respect for Lachlan "Lockie" Hernaman and his family.
Teams will return to the field for Round Five later this month.